Marmaduke has created a terrible chimera out of his Owner-Children.

Also, he is terrified of snakes and snake-shaped things.

Marmaduke's Neighbor-Man is extremely hard to impress.

Marmaduke doesn't understand that the purpose of putting your hands in wet cement is to provide proof of your existence as an individual in a harsh world that cares not for you or your well being. He thinks it's just pure vandalism because he is eternal and has no need to be remembered for he shall never be absent.

Marmaduke's Neighbor-Man is concerned that Marmaduke is going to ruin his raking when he should be concerned that Marmaduke has chosen him as the first victim.

The fact that Marmaduke makes his Owner-Boy tow him around even though it is undoubtedly far slower than if he just walked is quite humorous.

Not much to explain here but Marmaduke's face is truly horrifying.

This tiny soccer-boy doesn't seem to realize that Marmaduke is slowly consuming a player on the opposing team.

Or perhaps he doesn't care because he wants the advantage of the other team being down a player. Kids these days lack sportsmanship. And also fear of enormous dogs that eat children. They really should be more afraid of those.

A normal girl would be concerned that their dog has been severely injured but Marmaduke's Owner-Girl is relishing a rare opportunity to make fun of him.

This is what it's like when worlds collide.

I have a hard time believing Marmaduke's Owner-Family would bother wasting money on obedience school after 50 years of living with the monster.

Marmaduke and his Owner-Family are not worried about the hippopotamus eating that guy back there because they have Marmaduke on their side to protect them.

Marmaduke's Owner-Lady has no idea how chewing bones works.

Marmaduke's Owner-Children will never evade Marmaduke with poor hiding like that. They need to hide somewhere cool, like an old refrigerator.

Marmaduke's Owner-Man is putting ketchup on Marmaduke's food. Marmaduke seems very displeased at this.

Also, there are condiments for pets. I find this incredibly stupid.

This is not "Marmaduke is a very large dog" humor. This is just regular dog humor. And I refuse to explain it.